Top 5 Best Bed Bug Sprays (**2022 Review**)

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Home > Product Reviews > Best Bed Bug Killers For Your Home (Complete 2020 Guide) > Top 5 Best Bed Bug Sprays (**2022 Review**)

Looking for the best bed bug sprays that actually work? You’re in the right place!

In this Pest Strategies product review you can expect to learn:

  • Our #1 overall best bed bug spray
  • Tips about bed bugs and removal
  • What bed bug sprays are and how they work 
  • If sprays are effective in eliminating a bed bug infestation
  • Recommended sprays for homeowners

Click here to skip to our favorite spray!

Our Overall #1 Rated Pick

Bedlam Plus Bed Bug Spray

  • Kills adults and bed bug eggs
  • The “go-to” spray for professional exterminators
  • Works on multiple pests
  • Non-stain formulation

Out of the bed bug products we researched and reviewed, our top pick goes to Bedlam Plus.


It’s the “go-to” spray for pest control companies providing a water safe/non-stain option for bed bug removal.

It’s ingredients are specifically formulated to target pyrethroid resistant bed bugs that would normally be unphased by other products.

Something also important to note is that you can’t buy this stuff over the counter at your local garden/home store, so online is your only option for purchase.

Given the fact that this product is natural, tested to work, and easy to use, we’ve made it our top pick.

See below for the complete list of product we reviewed.

Reviewed By:
Ed Spicer

Ed has been working in the pest control industry for years helping 1,000's of homeowners navigate the world of insect and rodent management. He manages Pest Strategies now helping homeowners around the world!

Bedlam Bed Bug Spray

  • Best for Bed Bugs
  • Go-ToSpray for Professional Exterminators
  • Odor Not Terrible

FenvaStar EcoCap

  • Made from Vegetable Oil
  • Targets Multiple Bugs
  • Good Track Record

Proof Bed Bug Spray

  • Natural Alternative - Uses Neem Oil
  • Extremely Potent
  • Does Give Off Odor

Harris Bed Bug Spray

  • Odorless Spray
  • Lasting, Residual Effect
  • Can Be Hard to Setup Sprayer

BioAdvanced Plus Insect Killer Spray

  • Boasts 12 Month Protection Indoors from Insects
  • Claims to Kill Most Insects & 99% of Germs They Leave Behind
  • Wide Range of Reviews

Table Of Contents

    Top 5 Best Bed Bug Sprays

    Short on time or just want a quick answer?

    Check out our below list for a summary of our results. Keep on reading to learn more sprays and bed bugs!

    1. Bedlam Bed Bug Spray (the “go-to” spray for professionals)
    2. FenvaStar EcoCap (affordable and effective)
    3. Proof Bed Bug Spray (another natural alternative)
    4. Harris Bed Bug Spray (a decent spray but hard to operate)
    5. Bio Advanced Plus Insect Killer Spray (not for bed bugs but does work)

    The number of bed bugs have been steadily increasing over the last 50 years and are almost at epidemic levels (crazy!).

    Few people know about them or what to do when you find them.

    This article gives you some tips and suggestions on what bed bugs are and some of the best bed bug sprays available to combat them.

    What Are Bed Bugs?

    A bed bug goes through different life stages after hatching until becoming a fully grown adult. The young ones can be as small as a speck of dust and the white eggs can fit on a pin head. As they mature, they grow to about 5 mm in length and are the size of an apple seed.

    Adults turn red after they bite and inject an anticoagulant to stop the wound from healing, which is often the cause of the itchiness. The pests are nocturnal and you will only ever encounter them and get bitten late at night.

    The scary part is that some may not ever be aware that they have bed bugs. And, it takes months before you start to notice them.

    And when you do notice them… you’re already in trouble.

    Take a quick look at the video so that you have a really good understanding of what bed bugs look like.

    How Do I know If I have Bed Bugs?

    Most people begin to realize that they have a problem when they start to see bites that are very itchy. Other characteristic signs include seeing black fecal matter on the corners of the bed sheets or mattress.

    It’s not uncommon to see a red stain on your bed after you have crushed the ones that have recently fed. You can sometimes see the empty exoskeleton as they mature and shed their skins.

    Related Post:

    Want to know what bed bugs look like when they’re infesting your house? Check out this article for 53 images.

    A lot of people panic when they find they have bed bugs and decide to leave their bed and sleep in a spare room. Some even go as far as staying with a friend. These are the worst things that you can do. Bed bugs are hitchhikers and will use you as a carrier to move to different parts of your houses or elsewhere.

    The best thing is to stay calm and try to protect yourself from bites whilst simultaneously calling an exterminator.

    Bed Bug Warning

    If you do think you have bed bugs, we highly recommend first consulting with an exterminator before using sprays or any other method of bed bug control. Improper use can and will make your bed bug problem worse.

    Click here to see our #1 ranked exterminators  so you can get free quotes and begin the removal process.

    What Are Bed Bug Sprays?

    Bed bug spray is an insecticide based spray that works great for bed bugs that you can see and spray directly, but has no effect on the majority that you can’t.

    Most of the sprays will kill bed bugs that come into direct contact within a few minutes.

    Some sprays have a residual effect for up to 48 hours, which is great but can be hit or miss. Just because you spray an area, doesn’t mean it’s going to kill bed bugs.

    Sprays are effective if you’re strategic and use it regularly over a period of time. Use it in the places where they’re residing, such as in a suitcase or the corners of a mattress.

    Read Also: What’s the best bed bug trap?

    Compare Pest Control Companies Near You

    How Do Bed Bug Sprays Work?

    The best bed bug sprays use a chemical insecticides.

    The EPA describes in this article the various kinds of chemicals that exist and how they kill bed bugs. Pyrethroid is a common ingredient in some sprays.

    You also need to take care when you’re using it indoors since they can leave a bad odor and chemical residue on your clothes. This can be bad if you have children or pets.

    Take a look at the below video for a demonstration on how bed bug sprays work.

    Are Sprays Effective?

    Like everything else… it depends.

    Some bed bug sprays use outdated insecticides that bed bugs have grown resistant too.

    The vast majority of bed bugs hide deep in the crevices your mattress or room and sprays won’t reach them. This means that even the best bed bug sprays are only useful in a minor sense.

    You should do a thorough search of the house and identify the places where they are. Use a generous amount of spray regularly over a period of time. Yet, this is best used after consulting an exterminator to prevent the infestation from spreading.

    To learn more about bed bug removal, read our in-depth guide here.

    Pro Tip About Bed Bugs

    Due to the seriousness of a bed bug infestation, we at Pest Strategies highly recommend contacting an exterminator before doing any self treatment, which includes sprays.

    By using bed bug sprays,  you may end up making your bed bug problem worse by spreading bed bugs into new parts of your house.

    For example, if you spray a location where bed bugs are infested, you might kill some some, but the remaining ones will probably find a new hiding place.

    Bed Bug Spray Products Reviewed

    As a recap, here are the 5 sprays we looked at. Our #1 pick went to Bedlam, but check the others out to see if they are more suited to your needs.

    Of course, always be careful when handling chemicals (non-toxic or not).

    Related Articles

    Bedlam Plus Bed Bug Spray

    Bedlam plus is another top rated bed bug spray. Compared to other bed bug sprays, this product does have a strong odor. Bedlam also has ovicidal qualities as well as acting as an adulticide, which means it can kill eggs and adults on contact.

    Apply this product to the harborage areas as well as area you think the bed bugs are hiding and you should be in good shape.

    The Good And The Bad

    • Kills On Contact
    • Kills Eggs and Adult Bed Bugs
    • Odor is Not as Bad as Other Sprays
    • 2 Week Average Residual
    • Terrible Fumes, Similar to Other Bed Bug Sprays
    • May Irritate Your Skin On Contact
    Overall Rating

    FenvaStar Ecocap

    Our second pick is a newer formulation made by Rockwell Labs.

    It’s active ingredient is Esfenvalerate, which is a synthetic pyrethroid (aka a man-made insecticide).

    What’s special about FenvaStar,  is that it uses “microencapsulation”, which makes it easier to deliver a lethal does to your target bug although it doesn’t provide that satisfying “quick kill” knockdown you’ll find with the over the counter brands.

    It’s also worth noting that you’ll need a pump sprayer to apply the chemical to the bed bug hiding places in your home. Most are cheap and reusable (like this one), so you should have no problem getting one within your budget.

    The Good And The Bad

    • Uses "microencapsulation" technology to kill bugs
    • Residual Effect
    • Affordable price point
    • Will not immediately kill bed bugs

    Proof Bed Bug Spray

    Proof is an EPA-approved biopesticide with 5.5% neem oil as the active ingredient. Neem oil is a natural pesticide found in the seeds of a neem tree.

    Don’t let the word “natural” fool you however, this is still a potent solution that can and will harm you if inhaled by you or your children.

    You can use this environmentally friendly bug spray anywhere in your house and it claims to have residual effects that last for a week. Overall, users have found that it does help in reducing bed bugs in and around your house.

    Also, despite this product being environmentally friendly, it has an extremely potent odor that requires a fumigation mask and your windows open during use. For a full review of Proof Bed Bug Spray click here.

    The Good And The Bad

    • Organic Insecticide
    • Applies Well to Furniture And Other Belongings
    • Terrible Fumes, Similar To Bayer
    • Requires Consistent Application To Be Effective

    Harris Bed Bug Kller

    Harris is an odorless, non-stain liquid that you can use to spray your bed and furniture.

    You first need to pour the liquid into a smaller container. The product suggests that you use it regularly to get the best results.

    Harris usually has powerful effects whilst simultaneously leaving no odors or stains. Yet, (predictably) it doesn’t work against bed bugs that are hiding and may give you a false sense of security. It also requires prolonged periodic treatments. For a full review of Harris Bed Bug Killer click here.

    The Good And The Bad

    • Odorless spray
    • Residual effect that can last weeks
    • Slightly complicated setup
    • Requires Multiple Treatments And Combination Of Products To Be Effective

    Bio Advanced Plus Insect Killer Spray

    This one is a little non-traditional since it isn’t marketed directly as a bed bug spray.

    We found this spray doing a bit of digging and finding what has worked well for others.

    A number of users have compared this to Harris and Hot Shot finding it be more effective when applied to furniture, carpets, and other bed bug hiding areas.

    The one drawback from Bio Advanced spray is the hit or miss user reviews based on various experiences with using this product. Make sure to check the reviews to see if it could be a great solution for your specific issue.

    The Good And The Bad

    • Very Mild Odor
    • Claims 12 Month Protection of Indoor Spaces
    • Kills Variety of Bugs (Ants, Roaches, Bed Bugs, etc)
    • The Reviews are Mixed
    • Not Specifically Made for Bed Bugs
    Compare Pest Control Companies Near You