Top 3 Best Weed Killers For Your Grass (**2022 Review**)

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Home > Product Reviews > Weed Products > Top 3 Best Weed Killers For Your Grass (**2022 Review**)

Looking for the best weed killers for grass? Then you’re in the right place!

In this Pest Strategies product review you can expect to learn:

  • Our recommendations for weed killers in grass (as well as our top pick)
  • What weed killers are and how they work in grass
  • Which factors make a weed killer effective
  • The verdict on whether (or not) weed killers actually work

Our Overall #1 Rated Pick

Compare-N-Save Concentrate Grass and Weed Killer

  • Contains 41% glyphosate
  • Rainproof within 2 hours
  • Visible results within 2-4 days

Concentrate grass and weed killer is an all-around crowd pleaser: it’s affordable, effective, and fast-acting.

Here’s how it works: the spray is sold in a concentrated form which is mixed by hand with water. You’ll need an external spray nozzle to administer this spray across your lawn, and we recommend something like this which can be reused for several different purposes: Chapin 2-gallon multi-purpose sprayer.

Not only does this spray become resistant to rain in a matter of hours, but it begins to work weeding out your weeds within mere days. Customers report that it kills off the weeds in the yard between 2 and 4 days, meaning that by the end of a week, you should see a beautified lawn.

The solution is sold in four different size options: 16 oz, 32 oz, 1 gallon, and 2.5 gallon jugs. We recommend the gallon container for its volume-to-price ratio. With this size, you can mix 85 gallons of weed-killing spray over time, and cover up to 25,000 square feet of your lawn!

If you’re interested in learning more about weed killers or want to read more about the other products we considered, see below!

Reviewed By:
Ed Spicer

Ed has been working in the pest control industry for years helping 1,000's of homeowners navigate the world of insect and rodent management. He manages Pest Strategies now helping homeowners around the world!

Best Overall
Overall Rating
Best Service
Overall Rating

Compare-N-Save Grass and Weed Killer

  • More affordable than competitors
  • Rainproof in a matter of hours
  • Results within a week

Southern Ag 2,4-D Amine Weed Killer

  • Selective broadleaf weed control won't hurt desirable plants
  • Easy to mix
  • Fast-acting

Spectracide Weed & Grass Killer

  • Spray based, which makes it easier to apply around yard
  • Spray nozzle is included
  • Rainproof in minutes

Table Of Contents

    3 Best Weed Killers For Your Grass

    Short on time?  Take a look below for the top 5 in our list. Otherwise, check out our buying guide.

    What Is Weed Killer?

    Weeds, unfortunately, are the bane of every gardener’s existence. Even if you don’t have that much of a green thumb, you can agree that weeds are unsightly, and you’d really rather not have them junking up your lawn.

    Luckily, there are a few different types of chemical solutions that help landscapers and laymen alike with controlling these pesky plant intruders. Take a look below at the different types of weed killers out there.


    These weed killers are meant to be used before a new crop or flower is planted in a garden. This type of weed killer is used as a preventative measure against weeds, and is recommended for use a few days before planting of the targeted crops or flowers.

    Additionally, you can use preplant weed killers just before planting your targeted crops. As long as you’re using the weed killer BEFORE planting the flower or crop you actually want in your garden, you should see successful results.


    A pre-emergent herbicide acts as a prevention agent for new weeds to sprout through the soil.

    While it doesn’t kill existing weeds or stop the weed seeds from germinating, a pre-emergent weed killer works to prevent the emerging of the root systems, effectively hindering the weeds from steady growth.

    Without proper root growth, the plants are unable to branch out and grow properly!

    Dr. Justin Moss, a Turfgrass Specialist for Oklahoma State University, elaborates on pre-emergent weed control tactics he used as part of a demonstration held in 2015. Listen to what he has to say in the video below.


    On the other hand, post-emergent herbicides are used to kill weeds that have already grown in a certain area.

    Generally, these chemicals take the form of sprays which are doused onto the weeds to kill them on contact. The chemicals will seep into the root systems, weakening them at the core, ensuring that they won’t re-grow.

    What Makes a Weed Killer Good?

    There are a few key factors to consider when shopping around for a quality weed killer in your grass. Check out the sections below for a bit more insight.

    Concentrated vs. Ready-to-Use

    Many different weed killers will come shipped in a concentrated form, which is intended to be mixed by hand at the time of spraying. This gives the customer more control over the mixture, and the ability to either dilute or concentrate it higher, depending on his or her specific needs.

    In contrast, ready-to-use sprays are more uniform and more convenient for the user. They require no extra assembly, and often are much less prone to mixing mishaps. However, if your garden needs a bit more TLC from a weed killer, this may not be the most ideal option for you.

    Selective vs. Non-Selective

    A selective weed killer works to kill only the weeds within a sprayed area, honing in on the pesky plants and leaving the desired plants alone.

    A non-selective weed killer, however, does the opposite. These herbicides tend to wreck everything in their path, and it’s recommended if you choose a non-selective weed killer that you protect the plants you want to keep, because otherwise, you may be saying goodbye to them.

    For a quick explanation on how to safely apply non-selective herbicides around your grass, check out the video below.

    Do Weed Killers Work?

    Weed killers have been shown to be mostly effective.

    Due to shifting climates and terrains, there’s no 100% efficacy rate. However, when used properly and consistently, weed killers should eliminate your ugly weeds and beautify your lawn.

    Compare Pest Control Companies Near You

    Weed Killers for Grass Reviewed

    In the below section we break down each of our product recommendations in a little more detail.

    Related Articles

    Compare-N-Save Concentrate Grass and Weed Killer

    This solution is ideal for those who would like an all-in-one weed killer that simply works.

    Compare-N-Save developed a formula that works to target weeds and grasses that will leave your yard looking beautiful in a matter of days, not weeks. After just one application, the fast-acting formula sets to work—after just two hours, the solution is rain-proof, which eliminates the need for reapplication.

    Because of its concentrated state, the gallon jug can mix up to 85 gallons of prepared weed-killing spray over time. This should cover around 25,000 square feet, meaning that your grass will be protected from weeds for a long time coming!

    Compare-N-Save Concentrate Grass and Weed Killer requires the use of an external spray nozzle, which is sold separately.

    We recommend this product to those who want an all-around effective product to kill weeds in grass that won’t break the bank.

    The Good And The Bad

    • Product is affordable compared to competitors
    • Kills weeds in a matter of days
    • Becomes rainproof in hours
    • Comes in many sizes
    • Requires an external sprayer
    • Some soils need higher concentrations
    Overall Rating

    Southern Ag 2,4-D Amine Weed Killer

    What makes Southern AG 2,4-D Amine Weed Killer different from the rest is the fact that it’s a selective weed control substance, which is like liquid gold for gardeners.

    What does this mean, exactly?

    Essentially, it’s an herbicide developed to target only the weeds, while leaving desirable plants (like lawn turf and flower beds) alone. If you’ve got unsightly weeds crawling along your garden walls, this is the weed killer for you.

    This is a concentrated spray, meaning that the user must mix it manually. However, instructions are included with the spray which detail the exact ratio for proper mixture.

    Southern AG 2,4-D Amine Weed Killer requires the use of an external sprayer, which must be purchased separately. However, this can be repurposed for other things in the future—or even for future herbicidal sprays.

    The Good And The Bad

    • Selective weed control only targets weeds
    • Effective within a matter of days
    • Can be used in many different types of landscapes and turfs
    • Is sold in only one quart size
    • Requires the use of an external spray nozzle
    • Decreased effectiveness in hot climates

    Spectracide Weed & Grass Killer

    Spectracide has developed an easy-to-use spray which is indispensable for homeowners in their Weed & Grass Killer. This spray can be used on all types of terrain—grass, rocks, pavement, bricks, you name it!

    Another factor that separates this weed killer from the rest is that it’s fully ready-to-use upon arrival. There’s no mixing involved, and no separate spray nozzles required. You can simply spray away your weeds and watch them wilt!

    Within 15 minutes of application, the formula is rainproof. After three hours, the spray begins working to kill the weeds from the root upward, ensuring they won’t grow back.

    We recommend this weed killer to those who want an easy-breezy way to tackle a large number of weeds in their yard without the hassle of investing in a ton of extra equipment.

    The Good And The Bad

    • Ready to use with no mixing required
    • Comes with its own spray nozzle
    • Rainproof in minutes, not hours
    • Results can be seen in under a day
    • Some weeds only turn brown without dying
    • Some types of weeds need several applications
    Compare Pest Control Companies Near You